Liverpool reached the Champions League after a Dirk Kuyt goal deep into extra time gave them a 1-0 aggregate win over plucky Belgian rivals Standard Liege.
A round-up of Saturday's action in the Premier League.
Aston Villa returned to winning ways in stunning fashion as Ollie Watkins scored twice in a 3-0 away thumping of an abject Arsenal in drizzly north London on Sunday.
IMAGES from the English Premier League matches played on Saturday.
Champions Liverpool were ripped apart 7-2 at Aston Villa and Manchester United were humiliated 6-1 at home by Tottenham Hotspur on Sunday in one of the most astonishing days of Premier League results.
European champions Liverpool are second in their Champions League group - a point behind Napoli - and Klopp's side host Genk at Anfield.
Paris St Germain will play Borussia Dortmund and Barcelona were pitted against an unpredictable Napoli, while Chelsea were drawn against Bayern Munich. City, who will be at home in the second leg, have yet to beat the Spanish side with two draws and two defeats in their previous four meetings.
Chelsea won for the first time in six Premier League matches when they beat relegation-threatened Wolverhampton Wanderers 3-1 at home on Monday.
Holders Barcelona suffered a stunning 2-1 home defeat by Russia's Rubin Kazan while Liverpool lost by the same score to Olympique Lyon at Anfield on a night of high drama and late goals in the Champions League on Tuesday.
A summary of Wednesday's Champions League Round of 16, Second Leg, matches.
Two defeats and a draw from their first three matches in Group A have left Liverpool in the mire and needing a Houdini-like escape act to stay alive in the Champions League.
This is Real Madrid's third consecutive Champions League title.
A round-up of the UEFA Champions League last-16 first leg matches played on Tuesday.
Images from Tuesday's action in the Premier League
Champions Manchester City slipped to a shock first Premier League defeat of the season at Wolverhampton Wanderers on Saturday, while Manchester United's campaign of woe continued with a loss to Crystal Palace.
Five-times European champions Liverpool survived a late scare to move into the last 32 of the Europa League with a 1-0 win over Italian side Udinese on Thursday.
A summary of Tuesday night's matches in the UEFA champions League.
IMAGES from the Europa League matches played on Thursday.
Chelsea moved into the Premier League's top four as Mason Mount's superb first-half goal earned them a 1-0 win at champions Liverpool who suffered a club-record fifth straight home league defeat on Thursday.
The 2005 champions and last season's runners-up take on Besiktas in a must-win match on Tuesday knowing that even if they win their remaining three Group A games they could still fail to get through.
The strip made a memorable debut in the 7-0 thrashing of Maribor in the Champions League group stage, marking Liverpool's biggest ever away win in European competition.
Cody Gakpo scored his first goal for the club as they halted a dismal run
A round-up of Tuesday's action in the UEFA Champions League.
Beyond the handball incident, the Belgian champions were the better side on the night. Villa's World Cup-winning keeper Martinez was pressed into action early by Brugge, who had seven shots on target to the Premier League club's one, and made several key saves to keep his team in the game.
Roberto Firmino struck a stoppage-time winner as Liverpool beat Paris St Germain 3-2 at Anfield on Tuesday after Kylian Mbappe looked to have secured a point for the French side in a compelling Champions League Group C clash.
Liverpool eased into the Champions League quarter-finals after a superb strike by Fernando Torres gave last season's runners-up a 1-0 win at Inter Milan and a 3-0 aggregate victory. They join the other three English entrants, Manchester United, Arsenal and Chelsea, with AS Roma the only Italian side through.
Victor Boniface rattled the post with a powerful shot eight minutes after the restart as Leverkusen picked up where they had left off.
The reigning champions have won 53 and drawn 11 of those 64 games, scoring 169 goals and conceding 42 for a total of 170 points.
images from the UEFA Champions League matches played across Europe on Wednesday
Ajax wary of attacking Napoli.
Liverpool, inspired by two-goal Egyptian Mohamed Salah, took a big step towards the Champions League final with a 5-2 win over AS Roma in their semi-final, first leg at Anfield on Tuesday.
The first legs will be on Tuesday 24 and Wednesday 25 April, with the returns on May 1 and 2.
Al-Hilal wrapped up a place in the Asian Champions League semi-finals as a 2-0 win over fellow Saudi Pro League side Al-Ittihad in Jeddah on Tuesday completed a 4-0 aggregate success and set a world record with their 28th straight win in all competitions.
Vinicius Junior's second half tap-in steered Real Madrid to a 1-0 victory over Liverpool in the Champions League final on Saturday.
It is not yet clear how Liverpool will split their squad and whether Klopp will be present at both games.
A round-up of Tuesday's action in the UEFA Champions League.
Manchester City's Erling Haaland faces Borussia Dortmund and Barcelona's Robert Lewandowski meets Bayern Munich after the Champions League group-stage draw was made on Thursday.
The English champions will go through to the last 16 of the Champions League if they overcome Real Betis in Seville.
Jude Bellingham topped the men's overall voting, with the Real Madrid and England midfielder receiving 11,176 selections from his peers.